SCHEMBL22855979

SCHEMBL22855979

CCCCCCCC/C=C\CCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC

nearest known ligand 0.97

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CETP P11597 4/20 0.97
▸ THRB P10828 1/20 0.97
▸ MEN1 O00255 1/20 0.97
▸ KMT2A Q03164 1/20 0.97
▸ ASAH1 Q13510 2/20 0.76
▸ TP53 P04637 2/20 0.73
▸ CYP1A2 P05177 1/20 0.73
▸ CYP2D6 P10635 1/20 0.73
▸ MAPT P10636 1/20 0.73
▸ CYP2C9 P11712 1/20 0.73
▸ MAPK1 P28482 1/20 0.73
▸ CYP2C19 P33261 1/20 0.73
▸ DEGS1 O15121 1/20 0.72
▸ ASAH2 Q9NR71 2/20 0.69
▸ PLA2G4A P47712 4/20 0.67
▸ ALDH1A1 P00352 2/20 0.63
▸ KDM4E B2RXH2 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30167971 1.00 CETP (0.97) CETPTHRBMEN1KMT2AASAH1
SCHEMBL20152381 1.00 CETP (0.97) CETPTHRBMEN1KMT2AASAH1
SCHEMBL31276708 1.00 CETP (0.97) CETPTHRBMEN1KMT2AASAH1
SCHEMBL30915241 1.00 CETP (0.97) CETPTHRBMEN1KMT2AASAH1
SCHEMBL13587670 1.00 CETP (0.97) CETPTHRBMEN1KMT2AASAH1
SCHEMBL2734386 1.00 CETP (0.97) CETPTHRBMEN1KMT2AASAH1
SCHEMBL31277312 1.00 CETP (0.97) CETPTHRBMEN1KMT2AASAH1
SCHEMBL31277666 1.00 CETP (0.97) CETPTHRBMEN1KMT2AASAH1
SCHEMBL20450780 1.00 CETP (0.97) CETPTHRBMEN1KMT2AASAH1
SCHEMBL30498995 1.00 CETP (0.97) CETPTHRBMEN1KMT2AASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074989-A1 METHODS AND COMPOSITIONS FOR TREATING PANCREATIC DISEASE METANOIA BIO INC (US) 2025-03-06 — — US claimed
CN-119355184-A Parkinson disease biomarker, detection reagent and application 渤海(天津)医疗科技有限公司 2025-01-24 — — CN claimed
WO-2024216751-A1 RISK PREDICTION MODEL OPERATION MODULE, AND RISK PREDICTION SYSTEM FOR ACUTE CORONARY SYNDROME 南京品生医疗科技有限公司 2024-10-24 — — WO claimed
CN-118609835-A Construction method of coronary plaque stability prediction model based on ceramide 北京市心肺血管疾病研究所 2024-09-06 — — CN claimed
CN-118425358-A Use of lipid markers in detection of polycystic ovary syndrome 北京大学第三医院(北京大学第三临床医学院) 2024-08-02 — — CN claimed
US-20230324419-A1 METHOD FOR DIAGNOSING ACTING OF NERVONIC ACID AND USE THEREOF BAO FENG BIOTECH (BEIJING) CO., LTD (CN) 2023-10-12 — — US claimed
EP-4228667-A1 METHODS FOR REVERSING HEPATIC STEATOSIS Brightseed, Inc. (US) 2023-08-23 — — EP claimed
CN-116568319-A Method for reversing hepatic steatosis 布莱特西德公司 2023-08-08 — — CN claimed
US-20230093131-A1 ASSESSING AND TREATING ALCOHOL-ASSOCIATED LIVER DISEASE MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2023-03-23 — — US claimed
US-11529370-B2 Use of composition comprising stem cell-derived exosome as effective ingredient in strengthening skin barrier and improving skin barrier function EXOCOBIO INC. (KR) 2022-12-20 — — US claimed
US-20220362177-A1 CERAMIDE RATIOS AS PREDICTIVE AND THERAPEUTIC BIOMARKERS FOR LEUKEMIAS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2022-11-17 — — US claimed
WO-2022081567-A1 METHODS FOR REVERSING HEPATIC STEATOSIS BRIGHTSEED, INC. (US) 2022-04-21 — — WO claimed
CN-114354775-A Method for constructing and applying acute coronary syndrome diagnosis model 江苏品生医疗科技集团有限公司 2022-04-15 — — CN claimed
WO-2022033576-A1 METHOD FOR DIAGNOSING ACTING OF NERVONIC ACID, AND APPLICATION THEREOF 宝枫生物科技(北京)有限公司 2022-02-17 — — WO claimed
US-12629421-B2 Artificially synthesized sphingosine derivative lipoid monomer and use of same for delivering nucleic acid BEIJING BAISHIHEKANG PHARMACEUTICAL TECHNOLOGY (BSJPHARMA) CO., LTD (CN) 2026-05-19 — — US disclosed
CN-121914887-A Recombinant lipolytica saccharomyces cerevisiae engineering strain for producing nervonic acid and application 江南大学 2026-04-24 — — CN disclosed
US-12590320-B2 Cellular models of and therapies for ocular diseases REFLECTION BIOTECHNOLOGIES LIMITED (HK) 2026-03-31 — — US disclosed
WO-2022033576-A1 METHOD FOR DIAGNOSING ACTING OF NERVONIC ACID, AND APPLICATION THEREOF 宝枫生物科技(北京)有限公司 2022-02-17 — — WO disclosed
US-20210015767-A1 ARTIFICIALLY SYNTHESIZED SPHINGOSINE DERIVATIVE LIPOID MONOMER AND USE OF SAME FOR DELIVERING NUCLEIC ACID BEIJING BAISHIHEKANG PHARMACEUTICAL TECHNOLOGY (BSJPHARMA) CO., LTD (CN) 2021-01-21 — — US disclosed
US-20200407252-A1 METHODS AND USES OF DISSOLVED ORGANIC MATERIAL FRACTIONS FOR BINDING METAL IONS TRENT UNIVERSITY (CA) 2020-12-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629421-B2 Artificially synthesized sphingosine derivative lipoid monomer and use of same for delivering nucleic acid S1PR2, S1PR3, S1PR1 CETP 90/4885THRB 914/4885MEN1 1287/4885
US-20210015767-A1 ARTIFICIALLY SYNTHESIZED SPHINGOSINE DERIVATIVE LIPOID MONOMER AND USE OF SAME FOR DELIVERING NUCLEIC ACID SPHK2, SPHK1, S1PR2 CETP 80/4885THRB 4466/4885MEN1 579/4885
US-12590320-B2 Cellular models of and therapies for ocular diseases ALDH1A2, NR2E3, RBP4 CETP 2083/4885THRB 168/4885MEN1 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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