Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729801 | 1.00 | MEN1 (0.47) | MEN1KMT2ACASP2KDM4EPOLB | |
| SCHEMBL22526379 | 0.90 | MEN1 (0.45) | MEN1KMT2ACASP2GLP1R | |
| SCHEMBL20469991 | 0.88 | MEN1 (0.42) | MEN1KMT2ACASP2KDM4EPOLB | |
| SCHEMBL10048529 | 0.88 | CASP2 (0.55) | MEN1KMT2ACASP2CA12CA1 | |
| SCHEMBL22014884 | 0.86 | MEN1 (0.50) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL25466890 | 0.86 | MEN1 (0.50) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL23806133 | 0.86 | MEN1 (0.50) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL18908647 | 0.86 | MEN1 (0.50) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL24379925 | 0.86 | MEN1 (0.50) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL21965675 | 0.86 | MEN1 (0.44) | MEN1KMT2AKDM4EPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2020264490-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |