Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27142729 | 0.96 | CASP2 (0.52) | CASP2MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL11915802 | 0.96 | CASP2 (0.52) | CASP2MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL13644566 | 0.96 | CASP2 (0.52) | CASP2MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL25887649 | 0.96 | CASP2 (0.52) | CASP2MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL25885419 | 0.94 | CASP2 (0.50) | CASP2MEN1KMT2ATSHRHPGD | |
| SCHEMBL25908214 | 0.94 | CASP2 (0.50) | CASP2MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL12019333 | 0.94 | CASP2 (0.53) | CASP2MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL16365459 | 0.92 | TSHR (0.52) | CASP2MEN1KMT2ATSHRHPGD | |
| SCHEMBL29686983 | 0.92 | TSHR (0.52) | CASP2MEN1KMT2ATSHRHPGD | |
| SCHEMBL16329232 | 0.92 | CASP2 (0.48) | CASP2MEN1KMT2AHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9476087-B2 | Methods and compounds for detecting beta-lactamase activity | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-10-25 | — | — | US | disclosed |
| US-20140322739-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | UNIV NANYANG TECH (SG) | 2014-10-30 | — | — | US | disclosed |
| US-20120100555-A1 | Synthesis And Use Of Fluorophore-Tagged Antimalarials | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322739-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | LPO, MPO, GUSB | CASP2 1944/4885MEN1 3495/4885KMT2A 2396/4885 |
| US-20120100555-A1 | Synthesis And Use Of Fluorophore-Tagged Antimalarials | ABCC1, DHFR, GFPT1 | CASP2 969/4885MEN1 1858/4885KMT2A 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.