Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | PPARD | Q03181 | 5/20 | 0.58 |
| ▸ | PPARA | Q07869 | 5/20 | 0.58 |
| ▸ | F7 | P08709 | 5/20 | 0.58 |
| ▸ | F3 | P13726 | 5/20 | 0.58 |
| ▸ | TERT | O14746 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | FABP4 | P15090 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726983 | 0.89 | PPARG (0.55) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL31373181 | 0.88 | PPARG (0.62) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL9775730 | 0.84 | PPARG (0.36) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL31373182 | 0.83 | ALDH1A1 (0.66) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL5968107 | 0.82 | PPARG (0.64) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL9439470 | 0.81 | EP300 (0.54) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL17199787 | 0.81 | EP300 (0.54) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL11857561 | 0.81 | EP300 (0.54) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL15662569 | 0.81 | EP300 (0.54) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL5974158 | 0.81 | EP300 (0.54) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331927-B1 | TOPICAL COMPOSITION CONTAINING AT LEAST ONE VITAMIN D OR ONE VITAMIN D ANALOGUE AND AT LEAST ONE CORTICOSTEROID | LEO PHARMA AS (DK) | 2007-12-12 | — | — | EP | claimed |
| WO-2000044223-A9 | USE OF A FORMULATION FOR CONTROLLING EXPRESSION OF A TARGET GENE | SYNGENTA LTD (GB) | 2001-11-15 | — | — | WO | claimed |
| EP-1150563-A1 | USE OF A FORMULATION FOR CONTROLLING EXPRESSION OF A TARGET GENE | Syngenta Limited (GB) | 2001-11-07 | — | — | EP | claimed |
| EP-0746311-B1 | MEDICINAL PATCHES FOR PERCUTANEOUS ADMINISTRATION | PACIFIC CORP (KR) | 2001-07-11 | — | — | EP | claimed |
| WO-2000044223-A1 | USE OF A FORMULATION FOR CONTROLLING EXPRESSION OF A TARGET GENE | SYNGENTA LIMITED (GB) | 2000-08-03 | — | — | WO | claimed |
| EP-0487958-B1 | Transparent or semi-transparent cosmetic composition | KAO CORP (JP) | 1999-10-20 | — | — | EP | claimed |
| US-12139684-B2 | Method for manufacturing coal additive | KOREA JINTECH (KR) | 2024-11-12 | — | — | US | disclosed |
| US-20240207411-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | SEAPORT THERAPEUTICS, INC. | 2024-06-27 | — | — | US | disclosed |
| US-11975073-B2 | Lipid prodrugs of neurosteroids | PURETECH LYT, INC. (US) | 2024-05-07 | — | — | US | disclosed |
| US-11938137-B2 | Lipid prodrugs of mycophenolic acid and uses thereof | PURETECH LYT, INC. (US) | 2024-03-26 | — | — | US | disclosed |
| US-11883497-B2 | Lymphatic system-directing lipid prodrugs | PURETECH LYT, INC. (US) | 2024-01-30 | — | — | US | disclosed |
| EP-4306524-A2 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | PureTech LYT, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| US-20230338552-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | PURETECH LYT, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-4897214-A | Skin cleaning preparations containing a HLB 10-19 non-ionic emulsifier and a thickening agent | CRINOS INDUSTRIA FARMACOBIOLOGICA SPA. (IT) | 1990-01-30 | — | — | US | disclosed |
| EP-0166337-B1 | ELASTASE-CONTAINING HAIR CARE AGENT | Eisai Co., Ltd. (JP) | 1989-09-20 | — | — | EP | disclosed |
| US-4707293-A | Detergent composition | CRINOS INTERNATIONAL (CH) | 1987-11-17 | — | — | US | disclosed |
| US-4604139-A | Dual color ink composition | SAKURA COLOR PRODUCTS CORP. (JP) | 1986-08-05 | — | — | US | disclosed |
| EP-0166337-A1 | Elastase-containing hair care agent | Eisai Co., Ltd. (JP) | 1986-01-02 | — | — | EP | disclosed |
| US-4545819-A | Writing implement containing dual color ink composition | Sakupa Color Products Corp. (JP) | 1985-10-08 | — | — | US | disclosed |
| US-4490177-A | Dual color ink composition | SAKURA COLOR PRODUCTS CORP. (JP) | 1984-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230338552-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | CYP21A2, CYP46A1, CYP17A1 | PPARG 581/4885PPARD 1179/4885PPARA 807/4885 |
| US-11938137-B2 | Lipid prodrugs of mycophenolic acid and uses thereof | MALT1, CYP2B6, LIPA | PPARG 718/4885PPARD 1256/4885PPARA 621/4885 |
| US-11883497-B2 | Lymphatic system-directing lipid prodrugs | LIPA, MALT1, SGMS1 | PPARG 1409/4885PPARD 2083/4885PPARA 1346/4885 |
| US-20240207411-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | LIPA, MALT1, SGMS1 | PPARG 1409/4885PPARD 2083/4885PPARA 1346/4885 |
| US-11975073-B2 | Lipid prodrugs of neurosteroids | CYP21A2, CYP46A1, CYP17A1 | PPARG 581/4885PPARD 1179/4885PPARA 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.