SCHEMBL726983

SCHEMBL726983

CCCCCCCC/C(O)=C\CCCCCCCC=CCO

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.55
PPARD Q03181 5/20 0.55
PPARA Q07869 5/20 0.55
F7 P08709 5/20 0.55
F3 P13726 5/20 0.55
TERT O14746 3/20 0.55
PTPN1 P18031 3/20 0.55
HSD17B10 Q99714 3/20 0.55
FABP4 P15090 3/20 0.55
MAPT P10636 2/20 0.55
BLM P54132 2/20 0.55
LMNA P02545 2/20 0.55
CYP1A2 P05177 2/20 0.55
ALOX15 P16050 2/20 0.55
CYP2C19 P33261 2/20 0.55
DUSP3 P51452 2/20 0.55
FAAH O00519 2/20 0.55
CYP19A1 P11511 2/20 0.55
PTGS1 P23219 2/20 0.55
NR4A2 P43354 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31373181 0.93 PPARG (0.62) PPARGPPARDPPARAF7F3
SCHEMBL2285676 0.89 PPARG (0.58) PPARGPPARDPPARAF7F3
SCHEMBL31373182 0.87 ALDH1A1 (0.66) PPARGPPARDPPARAF7F3
SCHEMBL15662569 0.87 EP300 (0.54) PPARGPPARDPPARAF7F3
SCHEMBL11857561 0.87 EP300 (0.54) PPARGPPARDPPARAF7F3
SCHEMBL29969963 0.87 EP300 (0.54) PPARGPPARDPPARAF7F3
SCHEMBL9439470 0.87 EP300 (0.54) PPARGPPARDPPARAF7F3
SCHEMBL5974158 0.87 EP300 (0.54) PPARGPPARDPPARAF7F3
SCHEMBL17199787 0.87 EP300 (0.54) PPARGPPARDPPARAF7F3
SCHEMBL28981818 0.87 EP300 (0.54) PPARGPPARDPPARAF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210322299-A1 SKIN CARE FORMULATION EMBRYOGENESIS PTY LTD (AU) 2021-10-21 US claimed
EP-2575807-B1 FORMULATION BASED ON SULPIRIDE AND A SYNERGISTIC HOMEOPATHIC COMPOSITION FOR TREATMENT OF DEPRESSIVE SYNDROME NOVAK MAJA (HR) 2014-02-19 EP claimed
CN-1334700-A Application of preparation in controlling expression of target gene SINZETA LTD (GB) 2002-02-06 CN claimed
WO-2000044223-A9 USE OF A FORMULATION FOR CONTROLLING EXPRESSION OF A TARGET GENE SYNGENTA LTD (GB) 2001-11-15 WO claimed
EP-1150563-A1 USE OF A FORMULATION FOR CONTROLLING EXPRESSION OF A TARGET GENE Syngenta Limited (GB) 2001-11-07 EP claimed
WO-2000044223-A1 USE OF A FORMULATION FOR CONTROLLING EXPRESSION OF A TARGET GENE SYNGENTA LIMITED (GB) 2000-08-03 WO claimed
EP-0229899-B1 PAINTS DESOWAG Materialschutz GmbH (DE) 1991-07-03 EP claimed
US-20220184038-A1 STRUCTURED ENCAPSULATED SILICON-CONTAINING PARTICLES SISAF LIMITED (GB) 2022-06-16 US disclosed
EP-2575807-A1 FORMULATION BASED ON SULPIRIDE AND A SYNERGISTIC HOMEOPATHIC COMPOSITION FOR TREATMENT OF DEPRESSIVE SYNDROME Novak, Maja (HR) 2013-04-10 EP disclosed
WO-2011148203-A1 FORMULATION BASED ON SULPIRIDE AND A SYNERGISTIC HOMEOPATHIC COMPOSITION FOR TREATMENT OF DEPRESSIVE SYNDROME NOVAK MAJA (HR) 2011-12-01 WO disclosed
CN-101048137-A Spontaneously dispersible pharmaceutical composition NOVARTIS AG (CH) 2007-10-03 CN disclosed
US-7064108-B2 Topical ivermectin composition MERCK & CO., INC. (US) 2006-06-20 US disclosed
US-20050143325-A1 Topical invermectin composition SCHERING CORPORATION 2005-06-30 US disclosed
EP-1151120-A1 INDUCIBLE EXPRESSION SYSTEM FOR USE IN PLANTS Syngenta Limited (GB) 2001-11-07 EP disclosed
EP-1150563-A1 USE OF A FORMULATION FOR CONTROLLING EXPRESSION OF A TARGET GENE Syngenta Limited (GB) 2001-11-07 EP disclosed
WO-2001009357-A2 ETHANOL INDUCIBLE EXPRESSION SYSTEM SYNGENTA LIMITED (GB) 2001-02-08 WO disclosed
WO-2000044223-A1 USE OF A FORMULATION FOR CONTROLLING EXPRESSION OF A TARGET GENE SYNGENTA LIMITED (GB) 2000-08-03 WO disclosed
WO-2000044917-A1 INDUCIBLE EXPRESSION SYSTEM FOR USE IN PLANTS SYNGENTA LIMITED (GB) 2000-08-03 WO disclosed
US-5877209-A THE ANTIOXIDANT OR FREE RADICAL BLOCKING AGENT IS ASCORBIC-ACID, BUTYLATED HYDROXYTOLUENE (BHT), BUTYLATED HYDROXYANISOLE (BHA), A MIXTURE OF ASCORBIC ACID AND BHT OR BHA OR A BLEND OF TOCOPHEROLS AND ASCORBIC ACID. YUNIS ADEL A (US) 1999-03-02 US disclosed
US-5646098-A Carbonyl containing compounds and their derivatives as multi-functional fuel and lube additives EXXON CHEMICAL PATENTS INC (US) 1997-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220184038-A1 STRUCTURED ENCAPSULATED SILICON-CONTAINING PARTICLES SGMS1, SGMS2, SMURF1 PPARG 820/4885PPARD 953/4885PPARA 850/4885
US-20050143325-A1 Topical invermectin composition DPM1, CAPRIN1, COLGALT1 PPARG 1550/4885PPARD 2041/4885PPARA 2869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.