Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26351186 | 0.94 | OPRM1 (0.32) | OPRM1OPRL1 | |
| SCHEMBL23488913 | 0.93 | OPRM1 (0.31) | OPRM1OPRL1 | |
| SCHEMBL19336157 | 0.93 | OPRM1 (0.31) | OPRM1OPRL1 | |
| SCHEMBL25129589 | 0.89 | OPRM1 (0.35) | OPRM1OPRL1 | |
| SCHEMBL22363525 | 0.87 | OPRL1 (0.36) | OPRM1OPRL1 | |
| SCHEMBL23482195 | 0.87 | OPRM1 (0.32) | OPRM1OPRL1 | |
| SCHEMBL25102198 | 0.87 | OPRL1 (0.36) | OPRM1OPRL1 | |
| SCHEMBL18615568 | 0.86 | OPRM1 (0.31) | OPRM1OPRL1 | |
| SCHEMBL24538124 | 0.86 | OPRM1 (0.31) | OPRM1OPRL1 | |
| SCHEMBL23847242 | 0.86 | OPRM1 (0.34) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002289-A1 | MONOFUNCTIONAL INTERMEDIATES FOR LIGAND-DEPENDENT TARGET PROTEIN DEGRADATION | UNIV MICHIGAN REGENTS (US) | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002289-A1 | MONOFUNCTIONAL INTERMEDIATES FOR LIGAND-DEPENDENT TARGET PROTEIN DEGRADATION | MDM2, CD74, TNFSF10 | OPRM1 1527/4885OPRL1 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.