Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25129589 | 0.90 | OPRM1 (0.35) | OPRL1OPRM1SIGMAR1 | |
| SCHEMBL19122061 | 0.89 | HRH3 (0.36) | — | |
| SCHEMBL22857746 | 0.87 | OPRM1 (0.31) | OPRL1OPRM1 | |
| SCHEMBL23488913 | 0.87 | OPRM1 (0.31) | OPRL1OPRM1 | |
| SCHEMBL19336157 | 0.87 | OPRM1 (0.31) | OPRL1OPRM1 | |
| SCHEMBL25952878 | 0.87 | DRD2 (0.32) | OPRL1OPRM1 | |
| SCHEMBL29327076 | 0.83 | OPRM1 (0.34) | OPRL1OPRM1 | |
| SCHEMBL19997508 | 0.82 | DRD2 (0.33) | OPRL1OPRM1 | |
| SCHEMBL23482195 | 0.82 | OPRM1 (0.32) | OPRL1OPRM1 | |
| SCHEMBL26351186 | 0.82 | OPRM1 (0.32) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2024-02-29 | — | — | US | disclosed |
| US-20230331722-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-10-19 | — | — | US | disclosed |
| US-20230066136-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230066136-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | OPRL1 4479/4885OPRM1 4630/4885SIGMAR1 3159/4885 |
| US-20230331722-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | OPRL1 4479/4885OPRM1 4630/4885SIGMAR1 3159/4885 |
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | OPRL1 4479/4885OPRM1 4630/4885SIGMAR1 3159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.