Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GBA2 | Q9HCG7 | 14/20 | 0.35 |
| ▸ | GBA1 | P04062 | 9/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22857785 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1THRBHTT | |
| SCHEMBL6379260 | 0.91 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1THRBHTT | |
| SCHEMBL25777088 | 0.82 | SMN1; SMN2 (0.41) | ALDH1A1TDP1MEN1THRBHTT | |
| SCHEMBL458567 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TDP1MEN1THRBHTT | |
| SCHEMBL19132924 | 0.80 | SPHK1 (0.47) | ALDH1A1TDP1MEN1THRBHTT | |
| SCHEMBL14136582 | 0.80 | SPHK1 (0.47) | ALDH1A1TDP1MEN1THRBHTT | |
| SCHEMBL28862976 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TDP1SPHK2SPHK1SMN1; SMN2 | |
| SCHEMBL21786325 | 0.80 | — | — | |
| SCHEMBL17931427 | 0.80 | — | — | |
| SCHEMBL21401226 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021000041-A1 | IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY | Precision Nanosystems Inc. (CA) | 2021-01-07 | — | — | WO | disclosed |