SCHEMBL458567

SCHEMBL458567

CCCCCCCCCCOC1CCCOC1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
NAAA Q02083 2/20 0.40
GBA1 P04062 3/20 0.38
EPHX1 P07099 1/20 0.35
CES2 O00748 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SPHK2 Q9NRA0 1/20 0.34
SPHK1 Q9NYA1 1/20 0.34
MEN1 O00255 1/20 0.32
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28862976 0.98 ALDH1A1 (0.42) ALDH1A1TDP1NAAAGBA1EPHX1
SCHEMBL19053058 0.93 SMN1; SMN2 (0.40) ALDH1A1TDP1NAAASMN1; SMN2
SCHEMBL6379260 0.89 ALDH1A1 (0.46) ALDH1A1TDP1GBA1EPHX1SMN1; SMN2
SCHEMBL27688605 0.83 SPHK1 (0.31) SPHK1
SCHEMBL8926060 0.83 SPHK1 (0.34) ALDH1A1SPHK1
SCHEMBL27902525 0.83 SPHK1 (0.31) SPHK1
SCHEMBL8926054 0.83 SPHK1 (0.31) SPHK1
SCHEMBL9036799 0.83 SPHK1 (0.31) SPHK1
SCHEMBL22857763 0.81 ALDH1A1 (0.46) ALDH1A1TDP1GBA1SMN1; SMN2SPHK2
SCHEMBL22857785 0.81 ALDH1A1 (0.46) ALDH1A1TDP1GBA1SMN1; SMN2SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2177595-B2 Lubricating composition with good oxidative stability and reduced deposit formation AFTON CHEMICAL CORP (US) 2024-05-15 EP disclosed
US-10865357-B2 Lubricating oil composition with improved oxidation retention and reduced sludge and varnish formation PHILLIPS 66 COMPANY (US) 2020-12-15 US disclosed
US-10435609-B2 Hydrophilic ether carboxylic acids as lubricant for salt based drilling systems EMERY OLEOCHEMICALS GMBH (DE) 2019-10-08 US disclosed
EP-2109659-B1 DISPERSANT COMBINATION FOR IMPROVED TRANSMISSION FLUIDS LUBRIZOL CORP (US) 2019-06-12 EP disclosed
EP-3242919-B1 HYDROPHILIC ETHER CARBOXYLIC ACIDS AS LUBRICANT FOR SALT BASED DRILLING SYSTEMS EMERY OLEOCHEMICALS GMBH (DE) 2019-03-13 EP disclosed
US-10227545-B2 Additives for oilfield and industrial applications EMERY OLEOCHEMICALS GMBH (DE) 2019-03-12 US disclosed
EP-3242920-B1 NEW ADDITIVES FOR OILFIELD AND INDUSTRIAL APPLICATIONS EMERY OLEOCHEMICALS GMBH (DE) 2018-12-19 EP disclosed
WO-2018136735-A1 LUBRICATING OIL COMPOSITION WITH IMPROVED OXIDATION RETENTION AND REDUCED SLUDGE AND VARNISH FORMATION PHILLIPS 66 COMPANY (US) 2018-07-26 WO disclosed
US-20180208867-A1 LUBRICATING OIL COMPOSITION WITH IMPROVED OXIDATION RETENTION AND REDUCED SLUDGE AND VARNISH FORMATION PHILLIPS 66 COMPANY (US) 2018-07-26 US disclosed
US-20170342341-A1 NEW ADDITIVES FOR OILFIELD AND INDUSTRIAL APPLICATIONS BANK OF AMERICA, N.A., AS THE ADMINISTRATIVE AGENT 2017-11-30 US disclosed
EP-2177595-A1 Lubricating composition with good oxidative stability and reduced deposit formation Afton Chemical Corporation (US) 2010-04-21 EP disclosed
US-20090291865-A1 Controlled release of additives in gas turbine lubricating compositions AFTON CHEMICAL CORPORATION 2009-11-26 US disclosed
EP-2109659-A2 DISPERSANT COMBINATION FOR IMPROVED TRANSMISSION FLUIDS The Lubrizol Corporation (US) 2009-10-21 EP disclosed
US-20080188386-A1 Low Ash Controlled Release Gels THE LUBRIZOL CORPORATION (US) 2008-08-07 US disclosed
WO-2008094781-A2 DISPERSANT COMBINATION FOR IMPROVED TRANSMISSION FLUIDS THE LUBRIZOL CORPORATION (US) 2008-08-07 WO disclosed
US-7384896-B2 Controlled release of additive gel(s) for functional fluids THE LUBRIZOL CORPORATION (US) 2008-06-10 US disclosed
US-20080108531-A1 Viscosity Modifiers in Controlled Release Lubricant Additive Gels THE LUBRIZOL CORPORATION (US) 2008-05-08 US disclosed
US-20080015126-A1 Ashless Controlled Release Gels Gilbert, Teresan W. (US) 2008-01-17 US disclosed
US-20070049505-A1 Controlled release of additive gel(s) for functional fluids LUBRIZOL CORPORATION, THE 2007-03-01 US disclosed
US-20050137097-A1 Controlled release of additive gel(s) for functional fluids THE LUBRIZOL CORPORATION 2005-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080188386-A1 Low Ash Controlled Release Gels ASH2L, ASH1L, AHSA1 ALDH1A1 446/4885TDP1 3310/4885NAAA 1726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.