Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | STK17B | O94768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15507244 | 0.88 | ALDH1A1 (0.31) | ALDH1A1RAB9ASMN1; SMN2MAPTABCB1 | |
| SCHEMBL22858026 | 0.83 | ABCB1 (0.38) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22857987 | 0.81 | LMNA (0.31) | ALDH1A1RAB9ASMN1; SMN2MAPTPTGDR2 | |
| SCHEMBL23878619 | 0.81 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2MAPTTP53KMT2A | |
| SCHEMBL15507033 | 0.71 | ABCB1 (0.38) | ALDH1A1RAB9AMAPTNPC1TP53 | |
| SCHEMBL30992460 | 0.69 | ABCB1 (0.41) | MAPTTP53KMT2ACRHBPCRHR2 | |
| SCHEMBL15507057 | 0.68 | ALDH1A1 (0.35) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL30992642 | 0.68 | ABCB1 (0.38) | ALDH1A1KMT2ACRHBPCRHR2ABCB1 | |
| SCHEMBL15507032 | 0.65 | ABCB1 (0.36) | ALDH1A1MAPTABCB1KDM4EHPGD | |
| SCHEMBL32679879 | 0.65 | NPC1 (0.33) | RAB9ASMN1; SMN2PTGDR2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021000855-A1 | MALT1 INHIBITORS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2021-01-07 | — | — | WO | disclosed |