Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | POLA1 | P09884 | 1/20 | 0.49 |
| ▸ | POLD1 | P28340 | 1/20 | 0.49 |
| ▸ | TK1 | P04183 | 3/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18844511 | 1.00 | POLB (0.49) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL18844532 | 1.00 | POLB (0.49) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL19175297 | 1.00 | POLB (0.49) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL18844512 | 1.00 | POLB (0.49) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL24858820 | 0.95 | POLB (0.44) | POLBPOLA1POLD1TK1 | |
| SCHEMBL18855353 | 0.93 | POLB (0.49) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL22327114 | 0.92 | POLB (0.48) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL22327289 | 0.92 | POLB (0.48) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL22327117 | 0.92 | POLB (0.48) | POLBPOLA1POLD1TK1P2RY2 | |
| SCHEMBL24182625 | 0.91 | POLB (0.53) | POLBPOLA1POLD1TK1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002720-A1 | DNA SEQUENCING REACTION ADDITIVE | IsoPlexis Corporation | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002720-A1 | DNA SEQUENCING REACTION ADDITIVE | RNGTT, NSUN2, NT5C3B | POLB 18/4885POLA1 147/4885POLD1 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.