Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988081 | 0.87 | — | — | |
| SCHEMBL20581686 | 0.87 | SMN1; SMN2 (0.56) | SMYD3ALDH1A1MEN1MAPTHPGD | |
| SCHEMBL14199968 | 0.87 | SMN1; SMN2 (0.56) | SMYD3ALDH1A1MEN1MAPTHPGD | |
| SCHEMBL23652276 | 0.84 | ALDH1A1 (0.46) | SMYD3ALDH1A1MEN1MAPTHPGD | |
| SCHEMBL22858817 | 0.84 | L3MBTL1 (0.47) | MTNR1AMTNR1BGNAI3GNAO1GNAI1 | |
| SCHEMBL25662474 | 0.84 | ALDH1A1 (0.46) | SMYD3ALDH1A1MEN1MAPTHPGD | |
| SCHEMBL22859123 | 0.81 | EPHX2 (0.42) | SMYD3ALDH1A1EPHX2MEN1MAPT | |
| SCHEMBL11822035 | 0.79 | EPHX2 (0.54) | SMYD3ALDH1A1EPHX2MEN1MAPT | |
| SCHEMBL13573015 | 0.79 | EPHX2 (0.54) | SMYD3ALDH1A1EPHX2MEN1MAPT | |
| SCHEMBL20999175 | 0.79 | SMN1; SMN2 (0.63) | ALDH1A1MEN1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021000925-A1 | PYRROLO [2, 3-b] PYRAZINES AS HPK1 INHIBITOR AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2021-01-07 | — | — | WO | disclosed |