Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181120 | 0.95 | USP2 (0.53) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL157123 | 0.91 | HPGD (0.50) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL23424187 | 0.89 | HPGD (0.55) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL14364845 | 0.88 | HPGD (0.58) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL13160 | 0.88 | ESR2 (0.48) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL21142469 | 0.88 | HPGD (0.58) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL3616758 | 0.86 | HPGD (0.53) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL21128616 | 0.85 | HPGD (0.55) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL31028 | 0.83 | USP2 (0.56) | USP2SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL27669441 | 0.83 | USP2 (0.56) | USP2SMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-20220117228-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-21 | — | — | US | disclosed |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-18 | — | — | US | disclosed |
| US-20210000113-A1 | SPIRO CYCLOHEXANEDIONE DERIVATES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210000113-A1 | SPIRO CYCLOHEXANEDIONE DERIVATES AS HERBICIDES | CBR3, DDT, CBR1 | USP2 3265/4885SMN1; SMN2 4607/4885HPGD 132/4885 |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | USP2 2071/4885SMN1; SMN2 4727/4885HPGD 865/4885 |
| US-12043599-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | USP2 2071/4885SMN1; SMN2 4727/4885HPGD 865/4885 |
| US-20220117228-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | DDT, DHFR, CCNB3 | USP2 2241/4885SMN1; SMN2 4602/4885HPGD 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.