Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29736721 | 1.00 | ABCB1 (0.40) | ABCB1GPBAR1LMNAALDH1A1ALOX15 | |
| SCHEMBL22859644 | 0.90 | ALDH1A1 (0.42) | ABCB1GPBAR1LMNAALDH1A1KDM4E | |
| SCHEMBL23061286 | 0.88 | ABCB1 (0.43) | ABCB1GPBAR1LMNAALDH1A1ALOX15 | |
| SCHEMBL22859687 | 0.87 | ABCB1 (0.37) | ABCB1GPBAR1LMNAALDH1A1ALOX15 | |
| SCHEMBL22859613 | 0.84 | GPBAR1 (0.32) | GPBAR1SMN1; SMN2MAPT | |
| SCHEMBL23061050 | 0.81 | ABCB1 (0.39) | ABCB1GPBAR1LMNA | |
| SCHEMBL29736550 | 0.80 | TSHR (0.35) | LMNAALDH1A1TSHRKDM5AKDM4C | |
| SCHEMBL22859531 | 0.80 | TSHR (0.35) | LMNAALDH1A1TSHRKDM5AKDM4C | |
| SCHEMBL22859694 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL28549004 | 0.78 | RORC (0.31) | LMNAALDH1A1TSHRKDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689626-B | Substituted benzoyl-pyrazole compounds and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-112689626-A | Substituted benzoyl-pyrazole compounds and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2021-04-20 | — | — | CN | disclosed |
| WO-2021000736-A1 | SUBSTITUTED BENZOYL-PYRAZOLE COMPOUND, AND APPLICATION THEREOF IN AGRICULTURE | 东莞市东阳光农药研发有限公司 | 2021-01-07 | — | — | WO | disclosed |