Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 12/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.50 |
| ▸ | QDPR | P09417 | 2/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15165787 | 0.89 | FGFR1 (0.56) | TLR9TLR7TLR8QDPRFGFR1 | |
| SCHEMBL13122022 | 0.88 | CHRNB2 (0.46) | TLR9TLR7TLR8FGFR1FGFR2 | |
| SCHEMBL23010427 | 0.82 | TLR9 (0.54) | TLR9TLR7TLR8QDPRCHRNB2 | |
| SCHEMBL8265489 | 0.78 | BRD4 (0.48) | TLR9TLR7TLR8PARP1 | |
| SCHEMBL23010846 | 0.77 | QDPR (0.54) | TLR9TLR7TLR8QDPR | |
| SCHEMBL12761542 | 0.76 | TOP1 (0.54) | TLR9TLR7TLR8QDPRTNKS | |
| SCHEMBL13122023 | 0.76 | CHRNB2 (0.41) | TLR9TLR7TLR8FGFR1FGFR2 | |
| Hydrochloric Acid SCHEMBL10744669 | 0.76 | TOP1 (0.54) | TLR9TLR7TLR8QDPRTNKS | |
| SCHEMBL23122792 | 0.75 | QDPR (0.49) | TLR9TLR7TLR8QDPRKCNH2 | |
| SCHEMBL15837612 | 0.75 | PARP1 (0.43) | TLR9TLR7TLR8QDPRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030620-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021003314-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-01-07 | — | — | WO | disclosed |