Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.71 |
| ▸ | CDK2 | P24941 | 20/20 | 0.71 |
| ▸ | CCND1 | P24385 | 19/20 | 0.71 |
| ▸ | CDK6 | Q00534 | 19/20 | 0.71 |
| ▸ | CDK4 | P11802 | 6/20 | 0.65 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.65 |
| ▸ | CDK9 | P50750 | 5/20 | 0.65 |
| ▸ | CCND3 | P30281 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508843 | 1.00 | CCNE1 (0.71) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29507786 | 0.91 | CCNE1 (0.68) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL22860648 | 0.91 | CCNE1 (0.68) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29507753 | 0.87 | CCNE1 (0.76) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL22164779 | 0.87 | CCNE1 (0.76) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29508965 | 0.87 | CCNE1 (0.61) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL22860414 | 0.86 | CCNE1 (0.75) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29507883 | 0.86 | CCNE1 (0.75) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL22860530 | 0.85 | CCNE1 (0.73) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29508124 | 0.85 | CCNE1 (0.73) | CCNE1CDK2CCND1CDK6CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003314-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-01-07 | — | — | WO | disclosed |