Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29597975 | 1.00 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL1876366 | 0.84 | L3MBTL1 (0.69) | L3MBTL1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL1878693 | 0.83 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL1884667 | 0.83 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL1874109 | 0.83 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL8671223 | 0.83 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL22860752 | 0.81 | MAPT (0.58) | L3MBTL1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL29495143 | 0.81 | MAPT (0.58) | L3MBTL1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL15107476 | 0.78 | L3MBTL1 (0.74) | L3MBTL1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL1781479 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114514229-A | Antibacterial and antiparasitic quinoxaline-2, 3-diamine derivatives | 阿伯里斯特维斯大学 | 2022-05-17 | — | — | CN | disclosed |
| WO-2021001661-A1 | ANTIBACTERIAL AND ANTIPARASITIC QUINOXALINE-2,3-DIAMINE DERIVATIVES | ABERYSTWYTH UNIVERSITY (GB) | 2021-01-07 | — | — | WO | disclosed |