Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.50 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.50 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29495143 | 1.00 | MAPT (0.58) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL22860682 | 0.81 | L3MBTL1 (0.52) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29597975 | 0.81 | L3MBTL1 (0.52) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4548035 | 0.81 | EPHX1 (0.70) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL22860758 | 0.78 | RAB9A (0.71) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL29598234 | 0.78 | RAB9A (0.71) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL22860791 | 0.77 | TYMS (0.53) | KMT2AEGFRCYP3A4 | |
| SCHEMBL29495104 | 0.77 | TYMS (0.53) | KMT2AEGFRCYP3A4 | |
| SCHEMBL2374293 | 0.75 | MAPT (1.00) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL9613366 | 0.75 | KDM4E (0.75) | MAPTKDM4EMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114514229-A | Antibacterial and antiparasitic quinoxaline-2, 3-diamine derivatives | 阿伯里斯特维斯大学 | 2022-05-17 | — | — | CN | disclosed |
| WO-2021001661-A1 | ANTIBACTERIAL AND ANTIPARASITIC QUINOXALINE-2,3-DIAMINE DERIVATIVES | ABERYSTWYTH UNIVERSITY (GB) | 2021-01-07 | — | — | WO | disclosed |