SCHEMBL22860964

SCHEMBL22860964

CCCCCc1cc(O)c(C2C=C(C)CCC2)c2c1C(=O)OC(c1ccccc1)(c1ccccc1)O2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DAGLA Q9Y4D2 2/20 0.39
▸ NAAA Q02083 1/20 0.39
▸ CNR1 P21554 13/20 0.37
▸ CNR2 P34972 10/20 0.37
▸ LDHA P00338 2/20 0.37
▸ TRPM8 Q7Z2W7 2/20 0.37
▸ PPARG P37231 1/20 0.37
▸ ABHD12 Q8N2K0 3/20 0.36
▸ ABHD6 Q9BV23 3/20 0.36
▸ FAAH O00519 2/20 0.36
▸ GPR55 Q9Y2T6 2/20 0.36
▸ NR1I2 O75469 1/20 0.36
▸ GLRA1 P23415 1/20 0.36
▸ GPR183 P32249 1/20 0.36
▸ DRD3 P35462 1/20 0.36
▸ ENPP2 Q13822 1/20 0.36
▸ GPR18 Q14330 1/20 0.36
▸ TRPV1 Q8NER1 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22860894 0.87 DAGLA (0.39) DAGLANAAACNR1CNR2LDHA
SCHEMBL29661414 0.87 CNR1 (0.43) DAGLANAAACNR1CNR2LDHA
SCHEMBL22860842 0.87 CNR1 (0.43) DAGLANAAACNR1CNR2LDHA
SCHEMBL22860965 0.85 CNR1 (0.41) DAGLANAAACNR1CNR2LDHA
SCHEMBL29661416 0.85 CNR1 (0.41) DAGLANAAACNR1CNR2LDHA
SCHEMBL29661422 0.85 DAGLA (0.38) DAGLANAAACNR1CNR2LDHA
SCHEMBL22860856 0.85 DAGLA (0.38) DAGLANAAACNR1CNR2LDHA
SCHEMBL29661411 0.83 NAAA (0.58) DAGLANAAACNR1CNR2LDHA
SCHEMBL22860871 0.82 NAAA (0.41) DAGLANAAACNR1CNR2LDHA
SCHEMBL22860817 0.82 DAGLA (0.40) DAGLANAAACNR1CNR2LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3994129-A1 CANNABINOID DERIVATIVES Canopy Growth Corporation (CA) 2022-05-11 — — EP claimed
US-20220242844-A1 CANNABINOID DERIVATIVES CANOPY GROWTH CORPORATION (CA) 2022-08-04 — — US disclosed
EP-3994129-A1 CANNABINOID DERIVATIVES Canopy Growth Corporation (CA) 2022-05-11 — — EP disclosed
WO-2021000054-A1 CANNABINOID DERIVATIVES CANOPY GROWTH CORPORATION (CA) 2021-01-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220242844-A1 CANNABINOID DERIVATIVES CNR2, CNR1, FAAH DAGLA 214/4885NAAA 156/4885CNR1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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