Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.64 |
| ▸ | KDM4A | O75164 | 4/20 | 0.64 |
| ▸ | KDM4B | O94953 | 4/20 | 0.64 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.64 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24918932 | 0.88 | ADORA3 (0.61) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL26428366 | 0.87 | ADORA3 (0.60) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL15183057 | 0.86 | ADORA3 (0.56) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL23417847 | 0.85 | ADORA3 (0.66) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL19002444 | 0.82 | ADORA3 (0.73) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL29616747 | 0.81 | ADORA3 (0.57) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL15173226 | 0.81 | ADORA3 (0.57) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL24919461 | 0.81 | ADORA3 (0.62) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL15183138 | 0.81 | ADORA3 (0.52) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL15175064 | 0.81 | ADORA3 (0.50) | ADORA3KDM4AKDM4BKDM5BGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330240-A1 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | BIOHAVEN THERAPEUTICS LTD (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
| WO-2022246086-A1 | ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS | BIOHAVEN THERAPEUTICS LTD. (US) | 2022-11-24 | — | — | WO | disclosed |
| WO-2021102052-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |
| WO-2021003050-A2 | CD38-BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | CD2BP2, CD2, CD47 | ADORA3 4024/4885KDM4A 656/4885KDM4B 726/4885 |
| US-20230330240-A1 | TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS | HAVCR2, ACE2, EPCAM | ADORA3 2334/4885KDM4A 2005/4885KDM4B 1566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.