SCHEMBL22862134

SCHEMBL22862134

Cc1ccc(C(c2ccc(N3CC=CC3=O)cc2)c2ccc(N3C(=O)C=CC3=O)cc2)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 0.43
HSP90AA1 P07900 6/20 0.37
FAAH O00519 5/20 0.35
CCR6 P51684 3/20 0.34
G6PD P11413 1/20 0.32
TLR9 Q9NR96 1/20 0.32
TDP1 Q9NUW8 3/20 0.31
ALDH1A1 P00352 3/20 0.31
CACNA1B Q00975 2/20 0.31
APBA1 Q02410 2/20 0.31
LMNA P02545 2/20 0.31
APOBEC3G Q9HC16 1/20 0.31
NPSR1 Q6W5P4 2/20 0.31
PKM P14618 2/20 0.31
MAPK1 P28482 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
HPGD P15428 2/20 0.30
HTT P42858 2/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22862054 0.88 MGLL (0.56) MGLLHSP90AA1FAAHCCR6TDP1
SCHEMBL22880056 0.82 MGLL (0.50) MGLLHSP90AA1FAAHCCR6TDP1
SCHEMBL22880256 0.81 MGLL (0.34) MGLLHSP90AA1CACNA1BPKM
SCHEMBL22862147 0.77 MGLL (0.47) MGLLHSP90AA1FAAHCCR6TDP1
SCHEMBL23676376 0.76 MGLL (0.60) MGLLHSP90AA1FAAHCCR6TDP1
SCHEMBL22880332 0.76 MGLL (0.50) MGLLHSP90AA1FAAHCCR6TDP1
SCHEMBL22862091 0.75 MGLL (0.41) MGLLHSP90AA1FAAHCCR6TDP1
SCHEMBL22862092 0.74 MGLL (0.54) MGLLHSP90AA1FAAHCCR6TDP1
SCHEMBL6392634 0.73 MGLL (0.50) MGLLLMNAPKMMAPK1CA1
SCHEMBL22862085 0.72 MGLL (0.77) MGLLHSP90AA1FAAHCCR6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210003921-A1 COMPOUND, RESIN, COMPOSITION, AND FILM FORMING MATERIAL FOR LITHOGRAPHY USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210003921-A1 COMPOUND, RESIN, COMPOSITION, AND FILM FORMING MATERIAL FOR LITHOGRAPHY USING THE SAME COL1A1, MLLT3, F12 MGLL 1551/4885HSP90AA1 2396/4885FAAH 2256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.