Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22863374 | 0.86 | SMN1; SMN2 (0.50) | L3MBTL1SMN1; SMN2ALOX5APCCR1CCR5 | |
| SCHEMBL15004385 | 0.83 | L3MBTL1 (0.44) | L3MBTL1SMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL16132532 | 0.80 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL16132391 | 0.77 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL23918901 | 0.76 | CHRM2 (0.45) | L3MBTL1SMN1; SMN2ALOX5APCHRM2CYP3A4 | |
| SCHEMBL14275821 | 0.76 | ALOX5AP (0.66) | SMN1; SMN2ALOX5APALDH1A1CYP3A4KDM4E | |
| SCHEMBL31183050 | 0.72 | CYP1A2 (0.36) | L3MBTL1SMN1; SMN2ALDH1A1LMNACHRM2 | |
| SCHEMBL20809866 | 0.71 | SMN1; SMN2 (0.50) | L3MBTL1SMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL2018258 | 0.71 | SMN1; SMN2 (0.50) | L3MBTL1SMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL29080 | 0.70 | SMN1; SMN2 (0.58) | L3MBTL1SMN1; SMN2CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332466-B2 | Pyridinone-based epigenetic modifiers and uses thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210002272-A1 | PYRIDINONE-BASED EPIGENETIC MODIFIERS AND USES THEREOF | UNIV ILLINOIS (US) | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002272-A1 | PYRIDINONE-BASED EPIGENETIC MODIFIERS AND USES THEREOF | BRD1, BRD2, BRD3 | L3MBTL1 2387/4885SMN1; SMN2 3457/4885ALOX5AP 1989/4885 |
| US-11332466-B2 | Pyridinone-based epigenetic modifiers and uses thereof | BRD1, BRD2, BRD3 | L3MBTL1 2387/4885SMN1; SMN2 3457/4885ALOX5AP 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.