Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22863374 | 0.88 | SMN1; SMN2 (0.50) | CHRM2SMN1; SMN2L3MBTL1BLMSLC22A2 | |
| SCHEMBL13330619 | 0.79 | CHRM2 (0.49) | CHRM2SMN1; SMN2L3MBTL1BLMSLC22A2 | |
| SCHEMBL3660630 | 0.77 | TAAR1 (0.48) | CYP3A4ALOX15TSHRCYP2D6KMT2A | |
| SCHEMBL12862746 | 0.77 | SMN1; SMN2 (0.47) | CHRM2SMN1; SMN2L3MBTL1BLMSLC22A2 | |
| SCHEMBL16132367 | 0.76 | SMN1; SMN2 (0.52) | CHRM2SMN1; SMN2L3MBTL1BLMSLC22A2 | |
| SCHEMBL2018258 | 0.76 | SMN1; SMN2 (0.50) | CHRM2SMN1; SMN2L3MBTL1BLMSLC22A2 | |
| SCHEMBL20809866 | 0.76 | SMN1; SMN2 (0.50) | CHRM2SMN1; SMN2L3MBTL1BLMSLC22A2 | |
| SCHEMBL7894827 | 0.76 | SMN1; SMN2 (0.50) | CHRM2SMN1; SMN2L3MBTL1BLMSLC22A2 | |
| SCHEMBL2694787 | 0.76 | CHRM2 (0.54) | CHRM2SMN1; SMN2L3MBTL1BLMSLC22A2 | |
| SCHEMBL22863306 | 0.76 | L3MBTL1 (0.39) | CHRM2SMN1; SMN2L3MBTL1BLMSLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210315872-A1 | COMPOUNDS AND METHODS FOR EP300 or CBP MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315872-A1 | COMPOUNDS AND METHODS FOR EP300 or CBP MODULATION AND INDICATIONS THEREFOR | EP300, CREBBP, HDAC11 | CHRM2 1749/4885SMN1; SMN2 2517/4885L3MBTL1 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.