Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.55 |
| ▸ | CDK1 | P06493 | 4/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.55 |
| ▸ | CDK2 | P24941 | 4/20 | 0.55 |
| ▸ | CDK7 | P50613 | 3/20 | 0.55 |
| ▸ | CDK9 | P50750 | 3/20 | 0.55 |
| ▸ | CDK4 | P11802 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 4/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282854 | 0.87 | PAK4 (0.51) | AURKACDK1AURKBCDK2CDK9 | |
| SCHEMBL2285441 | 0.87 | MKNK2 (0.46) | AURKACDK1AURKBCDK2CDK7 | |
| SCHEMBL2284122 | 0.87 | KCNH3 (0.50) | AURKAAURKBCDK2CDK9CDK4 | |
| SCHEMBL2282479 | 0.86 | CDK2 (0.56) | AURKACDK1AURKBCDK2CDK7 | |
| SCHEMBL2284523 | 0.84 | AURKA (0.50) | AURKACDK1AURKBCDK2CDK7 | |
| SCHEMBL2284032 | 0.84 | CDK2 (0.46) | CDK1CDK2CDK7CDK9CDK4 | |
| SCHEMBL2283116 | 0.84 | CDK2 (0.50) | AURKACDK1AURKBCDK2CDK7 | |
| SCHEMBL2284194 | 0.82 | CDK2 (0.46) | AURKACDK1AURKBCDK2CDK7 | |
| SCHEMBL2286252 | 0.80 | CDK2 (0.37) | AURKACDK1AURKBCDK2CDK7 | |
| SCHEMBL2285956 | 0.79 | CDK2 (0.41) | AURKACDK1AURKBCDK2CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | AURKA 2085/4885CDK1 793/4885AURKB 3439/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | AURKA 2015/4885CDK1 857/4885AURKB 3377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.