Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | DHPS | P49366 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 3/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 3/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25791157 | 0.77 | AKT2 (0.43) | JAK2JAK1MAP4K1IDO1CDK2 | |
| SCHEMBL20850537 | 0.75 | CDK2 (0.43) | MAP4K1IDO1CDK2FLT3CCNA1 | |
| SCHEMBL21986864 | 0.73 | IDO1 (0.40) | MAP4K1IDO1CDK2CCNA1AXL | |
| SCHEMBL21986879 | 0.73 | NOS1 (0.42) | MAP4K1IDO1CDK2FLT3CCNA1 | |
| SCHEMBL24630980 | 0.71 | HIF1A (0.37) | IDO1 | |
| SCHEMBL21099841 | 0.70 | HRH4 (0.41) | HRH4HRH3 | |
| SCHEMBL22757498 | 0.69 | ESR2 (0.38) | MAP4K1IDO1CDK2FLT3CCNA1 | |
| SCHEMBL17030759 | 0.68 | IDO1 (0.41) | JAK2JAK1IDO1CDK2FLT3 | |
| SCHEMBL21938210 | 0.68 | IDO1 (0.38) | IDO1CDK2FLT3CCNA1AXL | |
| SCHEMBL4133588 | 0.68 | NOS1 (0.50) | JAK2JAK1IDO1CDK2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003161-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |