Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21986879 | 0.86 | NOS1 (0.42) | AKT2IDO1MAP4K1WEE1PKMYT1 | |
| SCHEMBL20850537 | 0.81 | CDK2 (0.43) | IDO1MAP4K1NOS1AXLCDK2 | |
| SCHEMBL21986864 | 0.79 | IDO1 (0.40) | IDO1MAP4K1WEE1PKMYT1NOS1 | |
| SCHEMBL22864052 | 0.77 | JAK2 (0.38) | IDO1MAP4K1NOS1AXLJAK2 | |
| SCHEMBL22757498 | 0.74 | ESR2 (0.38) | IDO1MAP4K1NOS1AXLCDK2 | |
| SCHEMBL10838630 | 0.73 | ROCK2 (0.39) | IDO1MAP4K1NOS1AXLROCK2 | |
| SCHEMBL3534803 | 0.73 | MAPT (0.52) | TDP1HSD17B10IDO1MAP4K1WEE1 | |
| SCHEMBL8404436 | 0.72 | IDO1 (0.46) | IDO1NOS1AXLMAPTJAK2 | |
| SCHEMBL21986783 | 0.72 | IDO1 (0.37) | IDO1MAP4K1NOS1AXLCDK2 | |
| SCHEMBL16647168 | 0.69 | IDO1 (0.47) | IDO1NOS1AXLMAPTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114733-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |