Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GRK3 | P35626 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24631013 | 0.84 | ADRB2 (0.52) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL24630960 | 0.84 | ADRB2 (0.52) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23870602 | 0.78 | TSHR (0.44) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL20763741 | 0.75 | MAPT (0.41) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL24631012 | 0.74 | ADRB2 (0.48) | KMT2ACYP2D6ADRB1ADRB2NFKB1 | |
| SCHEMBL12338365 | 0.73 | MAPT (0.48) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27328332 | 0.71 | KDM4E (0.46) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22864223 | 0.70 | ALDH1A1 (0.42) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17755389 | 0.69 | MAPT (0.45) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL19706018 | 0.68 | KDM4E (0.34) | KDM4EMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003161-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |