Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 14/20 | 0.48 |
| ▸ | FLT3 | P36888 | 7/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | BCR | P11274 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282943 | 0.86 | MKNK2 (0.51) | MKNK2FLT3MKNK1ABL1BCR | |
| SCHEMBL2283625 | 0.84 | PIK3CG (0.57) | MKNK2FLT3PIK3CGPIK3CAPIK3CB | |
| SCHEMBL2285192 | 0.83 | CDK2 (0.53) | PIK3CGPIK3CAPIK3CB | |
| SCHEMBL2285846 | 0.83 | MKNK2 (0.50) | MKNK2FLT3MKNK1MEN1ALDH1A1 | |
| SCHEMBL2279007 | 0.82 | MKNK2 (0.49) | MKNK2FLT3MKNK1 | |
| SCHEMBL2282939 | 0.81 | LIMK1 (0.48) | MKNK2FLT3MKNK1ABL1BCR | |
| SCHEMBL2286485 | 0.78 | MKNK2 (0.46) | MKNK2FLT3MKNK1ABL1BCR | |
| SCHEMBL2286244 | 0.77 | CDK2 (0.51) | ABL1BCRPIK3CGPIK3CAPIK3CB | |
| SCHEMBL2288652 | 0.77 | CDK2 (0.51) | ABL1BCRPIK3CGPIK3CAPIK3CB | |
| SCHEMBL2289567 | 0.76 | SMN1; SMN2 (0.47) | MKNK2FLT3MKNK1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | MKNK2 4101/4885FLT3 216/4885MKNK1 4404/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | MKNK2 4185/4885FLT3 211/4885MKNK1 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.