Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 9/20 | 0.45 |
| ▸ | BCR | P11274 | 9/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282939 | 0.89 | LIMK1 (0.48) | MKNK2SMN1; SMN2ABL1BCRMKNK1 | |
| SCHEMBL2287627 | 0.85 | PIK3CG (0.56) | MKNK2ABL1BCRFLT3PIK3CG | |
| SCHEMBL2286440 | 0.84 | ZAP70 (0.53) | PIK3CGPRKCAEGFR | |
| SCHEMBL2284219 | 0.82 | MKNK2 (0.47) | MKNK2KDM4EMEN1LMNAGAA | |
| SCHEMBL2282010 | 0.81 | MKNK2 (0.49) | MKNK2KDM4EMEN1LMNAGAA | |
| SCHEMBL2282943 | 0.79 | MKNK2 (0.51) | MKNK2ABL1BCRMKNK1FLT3 | |
| SCHEMBL2286458 | 0.78 | MKNK2 (0.48) | MKNK2MEN1GAAMAPTKMT2A | |
| SCHEMBL2280988 | 0.75 | CDK2 (0.52) | MKNK2ABL1BCRFLT3PIK3CG | |
| SCHEMBL2288481 | 0.75 | CCNT1 (0.52) | MEN1KMT2ASMN1; SMN2ABL1BCR | |
| SCHEMBL2286299 | 0.74 | CAMK2D (0.54) | GAAMAPTHTTABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | MKNK2 4101/4885KDM4E 1650/4885MEN1 458/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | MKNK2 4185/4885KDM4E 1720/4885MEN1 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.