Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.84 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.84 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.80 |
| ▸ | NT5E | P21589 | 5/20 | 0.78 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.72 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.69 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.68 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969947 | 0.91 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1GPR17ADORA3 | |
| SCHEMBL30969949 | 0.91 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1GPR17ADORA3 | |
| SCHEMBL17824354 | 0.91 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1GPR17ADORA3 | |
| SCHEMBL20277517 | 0.91 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1GPR17ADORA3 | |
| SCHEMBL20282633 | 0.91 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1GPR17ADORA3 | |
| SCHEMBL20282632 | 0.91 | TAS1R3 (1.00) | TAS1R3TAS1R1ADORA1GPR17ADORA3 | |
| SCHEMBL30150750 | 0.89 | ADORA1 (1.00) | TAS1R3TAS1R1ADORA1GPR17ADORA3 | |
| SCHEMBL23440052 | 0.88 | GPR17 (0.97) | TAS1R3TAS1R1ADORA1NT5EGPR17 | |
| SCHEMBL30969940 | 0.88 | GPR17 (0.97) | TAS1R3TAS1R1ADORA1NT5EGPR17 | |
| SCHEMBL21839754 | 0.88 | TAS1R3 (0.81) | TAS1R3TAS1R1ADORA1NT5EGPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001603-B2 | Modulators of 5′-nucleotidase, ecto and the use thereof | ARCUS BIOSCIENCES, INC. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20210002322-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ARCUS BIOSCIENCES, INC. | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11001603-B2 | Modulators of 5′-nucleotidase, ecto and the use thereof | ENTPD5, NT5C2, NT5E | TAS1R3 3936/4885TAS1R1 3895/4885ADORA1 40/4885 |
| US-20210002322-A1 | MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF | ENTPD5, NT5C2, NT5E | TAS1R3 3893/4885TAS1R1 3860/4885ADORA1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.