Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 known ✓ | P30542 | 8/20 | 1.00 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 7/20 | 0.77 |
| ▸ | ADORA2A known ✓ | P29274 | 5/20 | 0.77 |
| ▸ | ADORA2B known ✓ | P29275 | 3/20 | 0.75 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.85 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.85 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.72 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20277517 | 0.92 | TAS1R3 (1.00) | ADORA1TAS1R3TAS1R1GPR17ADORA3 | |
| SCHEMBL20282632 | 0.92 | TAS1R3 (1.00) | ADORA1TAS1R3TAS1R1GPR17ADORA3 | |
| SCHEMBL20282633 | 0.92 | TAS1R3 (1.00) | ADORA1TAS1R3TAS1R1GPR17ADORA3 | |
| SCHEMBL30969949 | 0.92 | TAS1R3 (1.00) | ADORA1TAS1R3TAS1R1GPR17ADORA3 | |
| SCHEMBL30969947 | 0.92 | TAS1R3 (1.00) | ADORA1TAS1R3TAS1R1GPR17ADORA3 | |
| SCHEMBL17824354 | 0.92 | TAS1R3 (1.00) | ADORA1TAS1R3TAS1R1GPR17ADORA3 | |
| SCHEMBL17023381 | 0.90 | ADORA1 (1.00) | ADORA1TAS1R3TAS1R1GPR17ADORA3 | |
| SCHEMBL17023380 | 0.90 | ADORA1 (1.00) | ADORA1TAS1R3TAS1R1GPR17ADORA3 | |
| SCHEMBL23440052 | 0.89 | GPR17 (0.97) | ADORA1TAS1R3TAS1R1GPR17ADORA3 | |
| SCHEMBL22866623 | 0.89 | TAS1R3 (0.84) | ADORA1TAS1R3TAS1R1GPR17ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250359548-A1 | METHODS OF IMPROVING STRESS TOLERANCE, GROWTH AND YIELD IN PLANTS | VALENT BIOSCIENCES LLC (US) | 2025-11-27 | — | — | US | disclosed |
| US-12402623-B2 | Methods of improving stress tolerance, growth and yield in plants | VALENT BIOSCIENCES LLC (US) | 2025-09-02 | — | — | US | disclosed |
| US-20240057597-A1 | METHODS OF IMPROVING STRESS TOLERANCE, GROWTH AND YIELD IN PLANTS | VALENT BIOSCIENCES LLC (US) | 2024-02-22 | — | — | US | disclosed |
| US-11812745-B2 | Method of improving stress tolerance, growth and yield in plants | VALENT BIOSCIENCES LLC (US) | 2023-11-14 | — | — | US | disclosed |
| EP-4106523-A1 | METHODS OF IMPROVING STRESS TOLERANCE, GROWTH AND YIELD IN PLANTS | Valent BioSciences LLC (US) | 2022-12-28 | — | — | EP | disclosed |