⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8937886 | 0.97 | — | — | |
| SCHEMBL28822522 | 0.91 | FFAR3 (0.35) | — | |
| SCHEMBL31276628 | 0.91 | FFAR3 (0.35) | — | |
| SCHEMBL30480315 | 0.87 | — | — | |
| SCHEMBL988825 | 0.87 | — | — | |
| SCHEMBL30199190 | 0.87 | — | — | |
| SCHEMBL2031585 | 0.87 | — | — | |
| SCHEMBL21230424 | 0.84 | CYP2C19 (0.42) | — | |
| SCHEMBL18618 | 0.84 | CYP2C19 (0.42) | — | |
| SCHEMBL27033107 | 0.80 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1052 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480003-A | Preparation method of fluoroalkylated quinoline diketone compound | 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) | 2024-08-13 | — | — | CN | claimed |
| CN-116640043-A | Synthesis method of 1-fluorocyclopropane carboxylic acid | 岳阳市康利医药化工有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-116535305-A | Preparation method and application of 1-fluorocyclobenzoic acid | 佛山奕安赛医药科技有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-110818552-B | Preparation method of 1-fluorocyclopropane carboxylic acid | 南京合巨药业有限公司 | 2022-04-22 | — | — | CN | claimed |
| EP-3241829-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2020-12-23 | — | — | EP | claimed |
| CN-110818552-A | Preparation method of 1-fluorocyclopropane carboxylic acid | 南京合巨药业有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-103261167-B | 6 of replacement, 6-condenses nitrogen-containing heterocycle compound and uses thereof | HOFFMAN-LA ROCHE LTD. (CH) | 2016-05-04 | — | — | CN | claimed |
| US-20150351403-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-10 | — | — | US | claimed |
| CN-103501780-B | Benzofuran-piperidine compounds | HOFFMAN-LA ROCHE LTD. (CH) | 2015-11-25 | — | — | CN | claimed |
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-12 | — | — | US | claimed |
| CN-102639516-A | 3-amino-5-phenyl-5, 6-dihydro-2H- [1,4] oxazine derivatives | HOFFMANN LA ROCHE | 2012-08-15 | — | — | CN | claimed |
| US-20120122929-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | claimed |
| WO-2012025557-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | claimed |
| CN-101384581-A | Benzoyl-piperidine derivatives as 5HT2/D3 modulators | HOFFMANN LA ROCHE (CH) | 2009-03-11 | — | — | CN | claimed |
| EP-0436348-B1 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LTD (GB) | 1996-11-13 | — | — | EP | claimed |
| US-5498750-A | Process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | claimed |
| EP-0533013-B1 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1995-10-18 | — | — | EP | claimed |
| US-5434303-A | Process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-18 | — | — | US | claimed |
| EP-0533013-A2 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1993-03-24 | — | — | EP | claimed |
| EP-0436348-A2 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LIMITED (GB) | 1991-07-10 | — | — | EP | claimed |