Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4823108 | 0.84 | CNR2 (0.41) | NPC1SLC6A4GRIN1GRIN2AGRIN2B | |
| SCHEMBL14002195 | 0.84 | CNR2 (0.41) | NPC1SLC6A4GRIN1GRIN2AGRIN2B | |
| SCHEMBL4823111 | 0.84 | CNR2 (0.41) | NPC1SLC6A4GRIN1GRIN2AGRIN2B | |
| SCHEMBL29617031 | 0.77 | ALDH1A1 (0.39) | NPC1ALDH1A1PDE7ASLC6A4SLC6A3 | |
| SCHEMBL29617028 | 0.77 | ALDH1A1 (0.39) | NPC1ALDH1A1PDE7ASLC6A4SLC6A3 | |
| SCHEMBL4822354 | 0.75 | ALDH1A1 (0.41) | NPC1ALDH1A1PDE7ASLC6A4SLC6A3 | |
| SCHEMBL4826928 | 0.71 | ALDH1A1 (0.41) | ALDH1A1CYP1A1CYP1B1ESR1AHR | |
| SCHEMBL15043707 | 0.71 | SLC6A3 (0.45) | SLC6A4SLC6A3S1PR1SLC6A2 | |
| SCHEMBL22867344 | 0.67 | CNR2 (0.44) | SLC6A4GRIN1GRIN2AGRIN2BS1PR1 | |
| SCHEMBL22872152 | 0.65 | S1PR1 (0.41) | NPC1ALDH1A1SLC6A4SLC6A3GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220259172-A1 | CHEMICAL INHIBITORS OF ID PROTEINS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | Universität Heidelberg (DE) | 2022-08-18 | — | — | US | disclosed |
| EP-3994123-A1 | CHEMICAL INHIBITORS OF ID PROTEINS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | Universität Heidelberg (DE) | 2022-05-11 | — | — | EP | disclosed |
| WO-2021001128-A1 | CHEMICAL INHIBITORS OF ID PROTEINS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | Universität Heidelberg (DE) | 2021-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220259172-A1 | CHEMICAL INHIBITORS OF ID PROTEINS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | ING2, IKZF1, DDIT3 | NPC1 3386/4885ALDH1A1 2934/4885PDE7A 4646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.