SCHEMBL22868909

SCHEMBL22868909

c1ccc(-c2cc(-n3c4ccccc4c4cc5c6c7ccccc7ccc6n(-c6ccccc6)c5cc43)nc3ccccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.41
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 6/20 0.40
HPGD P15428 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HTT P42858 3/20 0.39
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
ATM Q13315 1/20 0.38
MAPT P10636 3/20 0.35
MAPK1 P28482 2/20 0.35
PTGES O14684 1/20 0.33
IL1R1 P14778 1/20 0.32
ACACA Q13085 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PTGER4 P35408 1/20 0.32
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14233338 0.89 KDM4E (0.40) EGFRKDM4EALDH1A1HPGDTDP1
SCHEMBL18868190 0.89 KDM4E (0.36) EGFRKDM4EALDH1A1HPGDTDP1
SCHEMBL18868215 0.89 EGFR (0.35) EGFRKDM4EALDH1A1HPGDTDP1
SCHEMBL18868205 0.89 EGFR (0.35) EGFRKDM4EALDH1A1HPGDTDP1
SCHEMBL17299653 0.89 KDM4E (0.36) EGFRKDM4EALDH1A1HPGDTDP1
SCHEMBL18877124 0.88 EGFR (0.43) EGFRKDM4EALDH1A1HPGDTDP1
SCHEMBL21577560 0.88 EGFR (0.38) EGFRKDM4EALDH1A1HPGDTDP1
SCHEMBL26385734 0.87 KDM4E (0.40) EGFRKDM4EALDH1A1HPGDTDP1
SCHEMBL22868686 0.86 EGFR (0.42) EGFRKDM4EALDH1A1HPGDTDP1
SCHEMBL19677981 0.85 EGFR (0.36) EGFRKDM4EALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329107-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-10-12 US disclosed
US-20230329107-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-10-12 US disclosed
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-25 US disclosed
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-25 US disclosed
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-12-01 US disclosed
US-20210193933-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-06-24 US disclosed
US-20210005822-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165142-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE ELAVL1, LIMS1, ZNF436-AS1 EGFR 1389/4885KDM4E 1563/4885ALDH1A1 1311/4885
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, PIEZO1, LIMS1 EGFR 1565/4885KDM4E 3633/4885ALDH1A1 366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.