SCHEMBL22869008

SCHEMBL22869008

c1ccc(-c2nc3c(ccc4ccccc43)nc2-c2ccc3c4c(ccc3c2)-c2ccccc2C4(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.33
ALDH1A1 P00352 5/20 0.33
LMNA P02545 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
HTT P42858 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
NPY1R P25929 1/20 0.33
NPY2R P49146 1/20 0.33
KMT2A Q03164 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ATM Q13315 1/20 0.32
TLR9 Q9NR96 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
MEN1 O00255 1/20 0.31
MAOA P21397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22869009 1.00 KDM4E (0.33) KDM4EALDH1A1LMNASMN1; SMN2HTT
SCHEMBL22868659 0.97 KDM4E (0.32) KDM4EALDH1A1LMNASMN1; SMN2HTT
SCHEMBL22868647 0.94 KDM4E (0.34) KDM4EALDH1A1LMNASMN1; SMN2HTT
SCHEMBL22868645 0.94 KDM4E (0.34) KDM4EALDH1A1LMNASMN1; SMN2HTT
SCHEMBL22868636 0.91 LMNA (0.34) KDM4EALDH1A1LMNASMN1; SMN2HTT
SCHEMBL22868542 0.91 LMNA (0.34) KDM4EALDH1A1LMNASMN1; SMN2HTT
SCHEMBL22868996 0.88 L3MBTL1 (0.39) KDM4EALDH1A1LMNASMN1; SMN2HTT
SCHEMBL22868994 0.87 KDM4E (0.36) KDM4EALDH1A1LMNASMN1; SMN2HTT
SCHEMBL22868993 0.87 KDM4E (0.36) KDM4EALDH1A1LMNASMN1; SMN2HTT
SCHEMBL22869010 0.86 ADORA2A (0.32) KDM4EALDH1A1LMNASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210005822-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-07 US disclosed