SCHEMBL22869012

SCHEMBL22869012

c1ccc(-c2nc3ccc4ccccc4c3nc2-c2ccc3c4c(ccc3c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-4)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.32
ADORA1 P30542 2/20 0.32
MAPT P10636 3/20 0.31
KDM4E B2RXH2 3/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
MAOA P21397 1/20 0.31
LMNA P02545 3/20 0.31
HTT P42858 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
POLB P06746 1/20 0.31
HSP90AA1 P07900 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
GRK6 P43250 1/20 0.31
NPC1 O15118 1/20 0.31
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31
RAB9A P51151 1/20 0.31
SOS1 Q07889 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22869010 1.00 ADORA2A (0.32) ADORA2AADORA1MAPTKDM4EALDH1A1
SCHEMBL22868913 0.94 KDM4E (0.32) ADORA2AADORA1MAPTKDM4EALDH1A1
SCHEMBL22868906 0.94 KDM4E (0.32) ADORA2AADORA1MAPTKDM4EALDH1A1
SCHEMBL22868555 0.90 MAPT (0.32) ADORA2AADORA1MAPTKDM4EALDH1A1
SCHEMBL22868640 0.88 L3MBTL1 (0.39) ADORA2AADORA1KDM4EALDH1A1HPGD
SCHEMBL22186240 0.88 KDM4E (0.32) MAPTKDM4EALDH1A1HPGDMAOA
SCHEMBL22187688 0.88 KDM4E (0.32) MAPTKDM4EALDH1A1HPGDMAOA
SCHEMBL22868642 0.87 MAOA (0.34) ADORA2AADORA1KDM4EALDH1A1MAOA
SCHEMBL22868639 0.87 MAOA (0.34) ADORA2AADORA1KDM4EALDH1A1MAOA
SCHEMBL22869009 0.86 KDM4E (0.33) ADORA2AADORA1MAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210005822-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-07 US disclosed