Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | FABP7 | O15540 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29034926 | 1.00 | ALDH1A1 (0.58) | ALDH1A1F2TSHRFABP7FABP5 | |
| SCHEMBL17947657 | 0.87 | CPB1 (0.61) | ALDH1A1F2TSHRFABP7FABP5 | |
| SCHEMBL12986807 | 0.86 | ALDH1A1 (0.56) | ALDH1A1F2TSHRFABP7FABP5 | |
| SCHEMBL12986806 | 0.86 | ALDH1A1 (0.56) | ALDH1A1F2TSHRFABP7FABP5 | |
| SCHEMBL25245808 | 0.86 | ALDH1A1 (0.56) | ALDH1A1F2TSHRFABP7FABP5 | |
| SCHEMBL16117465 | 0.86 | TSHR (0.56) | ALDH1A1F2TSHRFABP7FABP5 | |
| SCHEMBL1838935 | 0.85 | ALDH1A1 (0.55) | ALDH1A1F2TSHRFABP7FABP5 | |
| SCHEMBL1838938 | 0.85 | ALDH1A1 (0.55) | ALDH1A1F2TSHRFABP7FABP5 | |
| SCHEMBL18562168 | 0.83 | ALDH1A1 (0.56) | ALDH1A1F2TSHRFABP7FABP5 | |
| SCHEMBL23790281 | 0.83 | CPB1 (0.51) | ALDH1A1F2TSHRFABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3759096-B1 | CD73 INHIBITORS | LILLY CO ELI (US) | 2022-02-16 | — | — | EP | disclosed |
| US-11028074-B2 | CD73 inhibitors | ELI LILLY AND COMPANY (US) | 2021-06-08 | — | — | US | disclosed |
| US-20210002257-A1 | CD73 INHIBITORS | ELI LILLY AND COMPANY | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11028074-B2 | CD73 inhibitors | ENTPD5, NT5E, ENTPD1 | ALDH1A1 280/4885F2 4757/4885TSHR 1601/4885 |
| US-20210002257-A1 | CD73 INHIBITORS | ENTPD5, NT5E, ENTPD1 | ALDH1A1 280/4885F2 4757/4885TSHR 1601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.