Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067645 | 0.83 | CA12 (0.66) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL18851155 | 0.81 | CA12 (0.64) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7908701 | 0.81 | POLB (0.68) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL18850964 | 0.79 | CA12 (0.70) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL31195191 | 0.78 | ALDH1A1 (0.57) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10680164 | 0.77 | ALDH1A1 (0.56) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL19777840 | 0.76 | CA12 (0.66) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9568652 | 0.76 | TGM2 (0.65) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL396730 | 0.76 | RXFP1 (0.62) | CA1CA2ALDH1A1LMNAPOLB | |
| SCHEMBL16057183 | 0.76 | CA1 (1.00) | CA12CA1CA2CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003399-A1 | ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS | ICONIC THERAPEUTICS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |