Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | HINT1 | P49773 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053623 | 1.00 | STING1 (0.52) | STING1HPGDPDE3BPDE3AADORA3 | |
| SCHEMBL6053627 | 1.00 | STING1 (0.52) | STING1HPGDPDE3BPDE3AADORA3 | |
| SCHEMBL8950587 | 1.00 | STING1 (0.52) | STING1HPGDPDE3BPDE3AADORA3 | |
| SCHEMBL98907 | 0.88 | ADORA3 (0.53) | STING1HPGDPDE3BPDE3AADORA3 | |
| SCHEMBL98906 | 0.88 | ADORA3 (0.53) | STING1HPGDPDE3BPDE3AADORA3 | |
| SCHEMBL12031117 | 0.88 | ADORA3 (0.53) | STING1HPGDPDE3BPDE3AADORA3 | |
| SCHEMBL4323450 | 0.88 | ADORA3 (0.53) | STING1HPGDPDE3BPDE3AADORA3 | |
| SCHEMBL18759056 | 0.88 | ADORA3 (0.53) | STING1HPGDPDE3BPDE3AADORA3 | |
| SCHEMBL9200583 | 0.88 | ADORA3 (0.53) | STING1HPGDPDE3BPDE3AADORA3 | |
| SCHEMBL13833321 | 0.88 | ADORA3 (0.53) | STING1HPGDPDE3BPDE3AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178133-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2021000380-A1 | MODIFIED NUCLEOSIDE, NUCLEOTIDE AND MODIFIED NUCLEIC ACID POLYMER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2021-01-07 | — | — | WO | disclosed |