SCHEMBL98907

SCHEMBL98907

Nc1nc2c(ncn2[C@@H]2O[C@H](CO)CC2O)c(=O)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.53
STING1 Q86WV6 3/20 0.52
PDE3B Q13370 1/20 0.52
PDE3A Q14432 1/20 0.52
HPGD P15428 2/20 0.51
HINT1 P49773 2/20 0.51
NT5E P21589 1/20 0.51
POLB P06746 1/20 0.50
TGM2 P21980 1/20 0.49
PNP P00491 1/20 0.49
TLR7 Q9NYK1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9200583 1.00 ADORA3 (0.53) ADORA3STING1PDE3BPDE3AHPGD
SCHEMBL16695880 1.00 ADORA3 (0.53) ADORA3STING1PDE3BPDE3AHPGD
SCHEMBL11929887 1.00 ADORA3 (0.53) ADORA3STING1PDE3BPDE3AHPGD
SCHEMBL98906 1.00 ADORA3 (0.53) ADORA3STING1PDE3BPDE3AHPGD
SCHEMBL4323450 1.00 ADORA3 (0.53) ADORA3STING1PDE3BPDE3AHPGD
SCHEMBL13833321 1.00 ADORA3 (0.53) ADORA3STING1PDE3BPDE3AHPGD
SCHEMBL18759056 1.00 ADORA3 (0.53) ADORA3STING1PDE3BPDE3AHPGD
SCHEMBL12031117 1.00 ADORA3 (0.53) ADORA3STING1PDE3BPDE3AHPGD
Phosphoric Acid SCHEMBL16213328 0.96 NT5E (0.54) ADORA3STING1PDE3BPDE3AHPGD
SCHEMBL23633225 0.92 ADORA3 (0.51) ADORA3STING1PDE3BPDE3AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 920 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
EP-4733408-A2 METHODS TO MINIMIZE BARCODE EXCHANGE 10X Genomics, Inc. (US) 2026-04-29 EP claimed
US-12473557-B2 Engineered guanylate kinase variant enzymes CODEXIS, INC. (US) 2025-11-18 US claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
US-20250170228-A1 TERMINALLY MODIFIED RNA ARES CAPITAL CORPORATION, AS AGENT 2025-05-29 US claimed
US-20250011859-A1 COMPOSITIONS AND METHODS FOR END TO END CAPTURE OF MESSENGER RNAS THE BROAD INSTITUTE, INC. (US) 2025-01-09 US claimed
US-20240425940-A1 COMPOSITIONS AND METHODS FOR ISOTHERMAL AMPLIFICATION OF NUCLEIC ACIDS SIRO DIAGNOSTICS, INC. 2024-12-26 US claimed
US-12163179-B2 Methods and systems to minimize barcode exchange 10X GEMOMICS, INC. (US) 2024-12-10 US claimed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US claimed
EP-4312942-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2024-02-07 EP claimed
US-20030008841-A1 Anti-HCV nucleoside derivatives F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) 2003-01-09 US claimed
WO-2002018404-A2 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C F. HOFFMANN-LA ROCHE AG (CH) 2002-03-07 WO claimed
US-20020019363-A1 Method for the treatment or prevention of flavivirus infections using nucleoside analogues VIROCHEM PHARMA INC. (CA) 2002-02-14 US claimed
EP-0090417-B1 PROCESS FOR PRODUCING 3'-DEOXYGUANOSINE Yamasa Shoyu Kabushiki Kaisha (JP) 1989-03-01 EP claimed
US-4594321-A Reacting guanine derivative with phosphate YAMASA SHOYU KABUSHIKI KAISHA (JP) 1986-06-10 US claimed
US-4594320-A Reacting guanine derivative with phosphate compound YAMASA SHOYU KABUSHIKI KAISHA (JP) 1986-06-10 US claimed
US-4434788-A 3'-DEOXYGUANOSINE OR 3'-DEOXYURIDINE ADMINISTERED WITH RADIATION YAMASA SHOYU KABUSHIKI KAISHA (JP) 1984-03-06 US claimed
EP-0090417-A2 Process for producing 3'-deoxyguanosine Yamasa Shoyu Kabushiki Kaisha (JP) 1983-10-05 EP claimed
EP-0045944-B1 ENHANCER OF ANTI-TUMOR EFFECT Yamasa Shoyu Kabushiki Kaisha (JP) 1983-08-31 EP claimed
EP-0045944-A1 Enhancer of anti-tumor effect Yamasa Shoyu Kabushiki Kaisha (JP) 1982-02-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019363-A1 Method for the treatment or prevention of flavivirus infections using nucleoside analogues NUDT1, HAVCR2, SLC28A1 ADORA3 1034/4885STING1 59/4885PDE3B 629/4885
US-20030008841-A1 Anti-HCV nucleoside derivatives PNP, HAVCR2, NUDT14 ADORA3 102/4885STING1 84/4885PDE3B 777/4885
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 ADORA3 558/4885STING1 2225/4885PDE3B 4771/4885
US-20250170228-A1 TERMINALLY MODIFIED RNA RNGTT, NSUN3, RNMT ADORA3 2884/4885STING1 660/4885PDE3B 3518/4885
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT ADORA3 4335/4885STING1 188/4885PDE3B 3393/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF ADORA3 3777/4885STING1 2314/4885PDE3B 4561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.