Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2198329 | 0.85 | RAB9A (0.38) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL4896123 | 0.85 | RAB9A (0.39) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL2287120 | 0.84 | RAB9A (0.37) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL10981815 | 0.77 | KDM5A (0.50) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL10994298 | 0.75 | CYP3A4 (0.54) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL5353450 | 0.71 | PDE10A (0.44) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL6404113 | 0.71 | QPCT (0.39) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL4891565 | 0.70 | MEN1 (0.47) | MAPTMEN1KMT2A | |
| SCHEMBL2199232 | 0.69 | MAPT (0.48) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL5632035 | 0.69 | NPC1 (0.43) | RAB9ALMNAMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977334-B2 | N-(3-{2-[3-(6-amino-benzimidazol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide; beta(3)-Adrenoceptor agonists; antidiabetic, obesity modulator, insulin resistance | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-12 | — | — | US | disclosed |