SCHEMBL228713

SCHEMBL228713

O=C(O)c1ccnc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.56
RAB9A P51151 2/20 0.56
KDM4A O75164 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
EGLN1 Q9GZT9 1/20 0.56
HIF1AN Q9NWT6 1/20 0.56
LMNA P02545 2/20 0.54
PSMD14 O00487 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.51
PDE10A Q9Y233 1/20 0.51
DHODH Q02127 3/20 0.50
POLB P06746 3/20 0.50
CYP1A2 P05177 2/20 0.50
ALDH1A1 P00352 2/20 0.50
GAA P10253 2/20 0.50
HPGD P15428 2/20 0.50
NSD2 O96028 1/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375172 1.00 KDM4E (0.56) KDM4ERAB9AKDM4AL3MBTL1EGLN1
SCHEMBL27589769 0.98 KDM4E (0.54) KDM4ERAB9AKDM4AL3MBTL1EGLN1
SCHEMBL29502894 0.98 KDM4E (0.54) KDM4ERAB9AKDM4AL3MBTL1EGLN1
Hydrochloric Acid SCHEMBL7310592 0.98 KDM4E (0.54) KDM4ERAB9AKDM4AL3MBTL1EGLN1
Hydrochloric Acid SCHEMBL30819457 0.98 KDM4E (0.54) KDM4ERAB9AKDM4AL3MBTL1EGLN1
Hydrochloric Acid SCHEMBL7308263 0.98 KDM4E (0.54) KDM4ERAB9AKDM4AL3MBTL1EGLN1
Hydrazine SCHEMBL27689567 0.96 KDM4E (0.53) KDM4ERAB9AKDM4AL3MBTL1EGLN1
Formaldehyde SCHEMBL27615678 0.96 KDM4E (0.53) KDM4ERAB9AKDM4AL3MBTL1EGLN1
Formic Acid SCHEMBL31505507 0.93 RAB9A (0.50) KDM4ERAB9AKDM4AL3MBTL1EGLN1
Hydrogen Sulfide SCHEMBL27865628 0.91 LMNA (0.51) KDM4ERAB9AKDM4AL3MBTL1EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1981 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713340-A2 COMPOSITIONS AND METHODS FOR PEPTIDE-BASED MODULATORS OF HUMAN PAPILLOMAVIRUS ONCOPROTEIN E6 Calico Life Sciences LLC (US) 2026-03-25 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
WO-2025102424-A1 COLD STORAGE SOLUTION AND USE THEREOF IN REDUCING ISCHEMIA-REPERFUSION INJURY OF CELLS, TISSUES, OR ORGANS 中山大学附属第三医院 2025-05-22 WO claimed
WO-2025102416-A1 APPLICATION OF QUINOLINE-4-CARBOXYLIC ACID IN PREPARATION OF ANTI-AGING PRODUCTS, AND LIVER PROTECTION AND LIVER REGENERATION PROMOTION PRODUCTS 广州日聚商贸发展有限公司 2025-05-22 WO claimed
US-20250160318-A1 CRYOPRESERVATION SOLUTION AND USE THEREOF IN REDUCING ISCHEMIA-REPERFUSION INJURY (IRI) OF CELL, TISSUE, OR ORGAN Third Affiliated Hospital, Sun Yat-sen University (CN) 2025-05-22 US claimed
CN-119912923-A Efficient bactericide for oil field and preparation method thereof 郑州德融科技有限公司 2025-05-02 CN claimed
CN-119409630-A Asymmetric polyfluoro-substituted 2,4' -biquinoline-4-amide derivative and preparation method and application thereof 郑州工业应用技术学院 2025-02-11 CN claimed
CN-119241790-B Covalent organic framework material and preparation method thereof 齐鲁理工学院 2025-02-11 CN claimed
CN-119241790-A Covalent organic framework material and preparation method thereof 齐鲁理工学院 2025-01-03 CN claimed
EP-4437319-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION Matterworks Inc (US) 2024-10-02 EP claimed
CN-1075720-A The quinoline that xenyl replaces SQUIBB & SONS INC (US) 1993-09-01 CN claimed
EP-0537191-A4 TREATMENT OF ORGAN TRANSPLANTATION REJECTION 1993-08-11 EP claimed
EP-0537191-A1 TREATMENT OF ORGAN TRANSPLANTATION REJECTION THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-04-21 EP claimed
US-5204329-A 4-Quinoline carboxylic acid derivatives DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-04-20 US claimed
WO-1991019498-A1 TREATMENT OF ORGAN TRANSPLANTATION REJECTION THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1991-12-26 WO claimed
US-5071987-A Quinoline dyes; colorfastness BASF AKTIENGESELLSCHAFT (DE) 1991-12-10 US claimed
EP-0397474-A2 Photosensitive composition KABUSHIKI KAISHA TOSHIBA (JP) 1990-11-14 EP claimed
US-4720494-A Anticholinergic eucatropine esters and antiperspirant use thereof THE GILLETTE COMPANY (US) 1988-01-19 US claimed
US-4670486-A Polymer composition pigmented with copper or nickel complexes of ligands containing a semicarbazone moiety CIBA-GEIGY CORPORATION (US) 1987-06-02 US claimed
EP-0031753-B1 2-(4-PIPERIDYL)-1-(4-QUINOLYL)-ETHANONE DERIVATIVES, INTERMEDIATES IN AND PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICINES PHARMUKA LABORATOIRES (FR) 1984-09-19 EP claimed