Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 20/20 | 0.58 |
| ▸ | CDK4 | P11802 | 16/20 | 0.58 |
| ▸ | AURKA | O14965 | 8/20 | 0.58 |
| ▸ | CDK7 | P50613 | 7/20 | 0.58 |
| ▸ | CDK9 | P50750 | 7/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.58 |
| ▸ | CDK1 | P06493 | 6/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.58 |
| ▸ | PLK1 | P53350 | 3/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | WEE1 | P30291 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288629 | 0.85 | CDK2 (0.70) | CDK2CDK4AURKACDK7CDK9 | |
| SCHEMBL2283630 | 0.84 | CDK2 (0.58) | CDK2CDK4AURKACDK7CDK9 | |
| SCHEMBL14562209 | 0.81 | CDK2 (0.74) | CDK2CDK4AURKACDK7CDK9 | |
| SCHEMBL2074508 | 0.79 | CDK2 (0.76) | CDK2CDK4AURKACDK7CDK9 | |
| SCHEMBL2289774 | 0.78 | CDK2 (0.58) | CDK2CDK4AURKACDK7CDK9 | |
| SCHEMBL2289719 | 0.78 | CDK2 (0.76) | CDK2CDK4AURKACDK7CDK9 | |
| SCHEMBL2278842 | 0.75 | CDK2 (0.56) | CDK2CDK4AURKACDK7CDK9 | |
| SCHEMBL4799735 | 0.74 | CDK2 (1.00) | CDK2CDK4AURKACDK7CDK9 | |
| SCHEMBL6269731 | 0.73 | CDK2 (0.64) | CDK2CDK4AURKACDK7CDK9 | |
| SCHEMBL6157713 | 0.72 | CDK2 (0.74) | CDK2CDK4AURKACDK7CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | CDK2 2065/4885CDK4 776/4885AURKA 2085/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | CDK2 2144/4885CDK4 818/4885AURKA 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.