Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.56 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22872947 | 0.84 | KCNN2 (0.57) | KCNN2KCNN3ALDH1A1NPSR1NR2F2 | |
| SCHEMBL4908801 | 0.84 | KCNN2 (0.59) | KCNN2KCNN3ALDH1A1NPSR1NR2F2 | |
| SCHEMBL4913903 | 0.84 | KCNN2 (0.59) | KCNN2KCNN3ALDH1A1NPSR1NR2F2 | |
| SCHEMBL4912379 | 0.84 | KCNN2 (0.59) | KCNN2KCNN3ALDH1A1NPSR1NR2F2 | |
| SCHEMBL4911365 | 0.82 | KCNN2 (0.57) | KCNN2KCNN3ALDH1A1NPSR1NR2F2 | |
| SCHEMBL22872866 | 0.81 | GBA1 (0.43) | KCNN3KMT2AMEN1LMNAADORA2A | |
| SCHEMBL183212 | 0.78 | KCNN2 (0.58) | KCNN2KCNN3ALDH1A1NPSR1NR2F2 | |
| SCHEMBL4910336 | 0.78 | ALDH1A1 (0.51) | KCNN2KCNN3ALDH1A1NPSR1NR2F2 | |
| SCHEMBL20568571 | 0.76 | POLB (0.56) | KCNN2KCNN3ALDH1A1NPSR1KMT2A | |
| SCHEMBL4216854 | 0.74 | NR2F2 (0.63) | KCNN2KCNN3ALDH1A1NPSR1NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009581-A1 | ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT | CHU NANTES (FR) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009581-A1 | ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT | CACNA1E, KCNA1, KCNT1 | KCNN2 19/4885KCNN3 35/4885ALDH1A1 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.