Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148493 | 0.81 | GRIK2 (0.56) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL13456337 | 0.80 | CYP1A2 (0.56) | ALDH1A1KDM4EP2RX4PTGER4 | |
| SCHEMBL8867584 | 0.80 | KDM4E (0.53) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL28948755 | 0.79 | DYRK1A (0.58) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL5186838 | 0.78 | KDM4E (0.66) | KDM4EPSEN1PSEN2APH1BNCSTN | |
| Diethylamine SCHEMBL15832827 | 0.78 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL5185105 | 0.78 | TSPO (0.49) | L3MBTL1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL3400464 | 0.78 | PSEN1 (0.41) | KDM4EMEN1KMT2APSEN1PSEN2 | |
| SCHEMBL2794274 | 0.78 | HPGD (0.49) | ALDH1A1KDM4EMAPTMEN1HPGD | |
| SCHEMBL2796905 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021004391-A1 | C-MYC PROTEIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州开拓药业股份有限公司 | 2021-01-14 | — | — | WO | disclosed |