Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22874125 | 0.80 | BRD4 (0.34) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL19984157 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL21698931 | 0.72 | CA12 (0.46) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7003667 | 0.70 | GLA (0.44) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL259485 | 0.69 | GLA (0.47) | ALDH1A1KDM4EMEN1KMT2AGLA | |
| SCHEMBL14344805 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KDM4EGLASMN1; SMN2KEAP1 | |
| SCHEMBL26579714 | 0.69 | GLA (0.52) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL3673101 | 0.68 | GLA (0.46) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL13690376 | 0.68 | ALDH1A1 (0.48) | ALDH1A1KDM4EGLASMN1; SMN2KEAP1 | |
| SCHEMBL24784205 | 0.68 | KMT2A (0.49) | ALDH1A1MEN1KMT2ARAB9AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055299-B1 | PYRIMIDINE HYDROXY AMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ACETYLON PHARMACEUTICALS INC (US) | 2021-01-06 | — | — | EP | disclosed |