Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811457 | 0.91 | GLA (0.44) | KMT2AMEN1RAB9ANPC1GLA | |
| SCHEMBL7003667 | 0.87 | GLA (0.44) | KMT2AMEN1RAB9ANPC1GLA | |
| SCHEMBL8190981 | 0.83 | KMT2A (0.46) | KMT2AMEN1RAB9ANPC1GLA | |
| SCHEMBL10254267 | 0.80 | GLA (0.53) | KMT2AMEN1RAB9AGLASMN1; SMN2 | |
| SCHEMBL259485 | 0.80 | GLA (0.47) | KMT2AMEN1GLASMN1; SMN2ALDH1A1 | |
| SCHEMBL26579714 | 0.80 | GLA (0.52) | KMT2AMEN1RAB9AGLASMN1; SMN2 | |
| SCHEMBL22282225 | 0.79 | TSHR (0.47) | KMT2AMEN1RAB9ANPC1GLA | |
| SCHEMBL29889549 | 0.78 | SMN1; SMN2 (0.44) | KMT2AMEN1GLASMN1; SMN2ALDH1A1 | |
| SCHEMBL3673101 | 0.78 | GLA (0.46) | KMT2AMEN1RAB9AGLASMN1; SMN2 | |
| SCHEMBL11243579 | 0.77 | THRB (0.45) | KMT2AMEN1ALDH1A1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261296-A1 | COMPOUNDS THAT BIND NON-CANONICAL G-QUADRUPLEX STRUCTURES AND METHODS OF MAKING AND USING THE SAME | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-12-15 | — | — | WO | disclosed |