Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22874322 | 1.00 | DGAT1 (0.38) | DGAT1KDM4EPKMTSHRTDP1 | |
| SCHEMBL2282604 | 0.82 | DGAT1 (0.45) | DGAT1TDP1MEN1KMT2A | |
| SCHEMBL4069477 | 0.81 | DGAT1 (0.38) | DGAT1KDM4EPKMTSHRTDP1 | |
| SCHEMBL806956 | 0.81 | DGAT1 (0.38) | DGAT1KDM4EPKMTSHRTDP1 | |
| SCHEMBL21492510 | 0.79 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL19881213 | 0.79 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL13304012 | 0.79 | DGAT1 (0.37) | DGAT1KDM4EPKM | |
| SCHEMBL22874327 | 0.79 | TSHR (0.34) | TSHRTDP1MEN1KMT2A | |
| SCHEMBL22874323 | 0.79 | TSHR (0.34) | TSHRTDP1MEN1KMT2A | |
| SCHEMBL18878199 | 0.77 | DGAT1 (0.35) | DGAT1PKMTSHRTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007386-A1 | INDANES AS PD-L1 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2021-01-14 | — | — | WO | disclosed |