SCHEMBL18878199

SCHEMBL18878199

CCCC(C)(NC)C(=O)OC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.35
CA1 P00915 2/20 0.33
CA12 O43570 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ELANE P08246 1/20 0.33
THRB P10828 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
CA2 P00918 1/20 0.31
TSHR P16473 2/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22294160 0.86 MAPT (0.44) LMNACA1MEN1MAPTKMT2A
SCHEMBL4069477 0.82 DGAT1 (0.38) DGAT1ALDH1A1CA1CA12CA7
SCHEMBL806956 0.82 DGAT1 (0.38) DGAT1ALDH1A1CA1CA12CA7
SCHEMBL22838156 0.81 ELANE (0.35) DGAT1ALDH1A1LMNAHSD17B10CA1
SCHEMBL10296094 0.81 DGAT1 (0.34) DGAT1TSHR
SCHEMBL18884435 0.81 LMNA (0.38) DGAT1ALDH1A1LMNAHSD17B10CA1
SCHEMBL16222807 0.78 ALDH1A1 (0.36) DGAT1ALDH1A1LMNAHSD17B10MEN1
SCHEMBL14562924 0.78 ALDH1A1 (0.36) DGAT1ALDH1A1LMNAHSD17B10MEN1
SCHEMBL19906424 0.77 CYP3A4 (0.37) ALDH1A1LMNAHSD17B10MEN1KMT2A
SCHEMBL3457184 0.77 NAALAD2 (0.42) ALDH1A1LMNAHSD17B10MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3756464-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2020-12-30 EP disclosed
EP-3151669-B1 USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2020-10-28 EP disclosed
US-20200283398-A1 USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2020-09-10 US disclosed
EP-2735444-B1 Lithographic printing plate precursor for newspaper printing and method for producing the same, and plate making method of lithographic printing plate FUJIFILM CORP (JP) 2018-02-28 EP disclosed
US-20170144980-A1 USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2017-05-25 US disclosed
US-20170144980-A1 USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2017-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200283398-A1 USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI CYP51A1, DPM1, NOX1 DGAT1 1994/4885ALDH1A1 1574/4885LMNA 4512/4885
US-20170144980-A1 USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI CYP51A1, DPM1, NOX1 DGAT1 1994/4885ALDH1A1 1574/4885LMNA 4512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.