Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880191 | 0.82 | LMNA (0.54) | LMNAKMT2ABRD9RXFP1METAP1 | |
| SCHEMBL5227380 | 0.81 | SMN1; SMN2 (0.47) | JUNNFKB1NFKB2RELAKMT2A | |
| SCHEMBL5229725 | 0.80 | MEN1 (0.45) | LMNAKMT2ABRD9RXFP1METAP1 | |
| SCHEMBL5228223 | 0.80 | MDM4 (0.62) | LMNAKMT2AALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL3716281 | 0.79 | P4HTM (0.53) | LMNAKMT2AMETAP1ALDH1A1RAB9A | |
| SCHEMBL29768539 | 0.79 | P4HTM (0.53) | LMNAKMT2AMETAP1ALDH1A1RAB9A | |
| SCHEMBL2384644 | 0.78 | HDAC1 (0.47) | KMT2ARXFP1METAP1BRD4LCK | |
| SCHEMBL2385252 | 0.78 | MEN1 (0.55) | LMNAKMT2AMETAP1ALDH1A1RAB9A | |
| SCHEMBL2829176 | 0.78 | POLB (0.56) | KMT2ARXFP1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL23517785 | 0.78 | CYP17A1 (0.41) | JUNNFKB1NFKB2RELALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007313-A1 | WNT ACTIVATORS AND METHODS OF USE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-01-14 | — | — | WO | disclosed |